Anchored HTML File of EIDs

	WEB-based GEne SeT AnaLysis Toolkit

	*Translating gene lists into biological insights...*

User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID.
The second row lists the following statistics:

C: the number of reference genes in the category
O: the number of genes in the gene set and also in the category
E: the expected number in the category
R: ratio of enrichment
rawP: p value from hypergeometric test
adjP: p value adjusted by the multiple test adjustment

Finally, genes in the pathway are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:KEGG pathway Name:Lysosome ID:04142
C=121; O=2; E=0.14; R=14.55; rawP=0.0084; adjP=0.0228
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000064601	NA	CTSA	cathepsin A	5476	ENSG00000064601
2	ENSG00000071553	NA	ATP6AP1	ATPase, H+ transporting, lysosomal accessory protein 1	537	ENSG00000071553

Database:KEGG pathway Name:Protein processing in endoplasmic reticulum ID:04141
C=165; O=2; E=0.19; R=10.67; rawP=0.0152; adjP=0.0228
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000089248	NA	ERP29	endoplasmic reticulum protein 29	10961	ENSG00000089248
2	ENSG00000109501	NA	WFS1	Wolfram syndrome 1 (wolframin)	7466	ENSG00000109501

Database:KEGG pathway Name:Metabolic pathways ID:01100
C=1130; O=4; E=1.28; R=3.12; rawP=0.0392; adjP=0.0392
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000174684	NA	B3GNT1	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1	11041	ENSG00000174684
2	ENSG00000124155	NA	PIGT	phosphatidylinositol glycan anchor biosynthesis, class T	51604	ENSG00000124155
3	ENSG00000113161	NA	HMGCR	3-hydroxy-3-methylglutaryl-CoA reductase	3156	ENSG00000113161
4	ENSG00000071553	NA	ATP6AP1	ATPase, H+ transporting, lysosomal accessory protein 1	537	ENSG00000071553

WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).